Ocular and eyelid involvement in collagen vascular diseases. Part I. Sjögren syndrome and systemic lupus erythematosus

Clin Dermatol. 2024 Jan-Feb;42(1):3-8. doi: 10.1016/j.clindermatol.2023.10.007. Epub 2023 Oct 18.

Abstract

Collagen vascular disease is a heterogeneous group of autoimmune diseases that affect multiple organ systems. Sjögren syndrome, dermatomyositis, scleroderma, systemic lupus erythematosus, and sarcoidosis are collagen vascular diseases that often present with characteristic cutaneous manifestations. Although less known, various ocular manifestations that affect both external and internal structures of the eye can be seen in these conditions. Multidisciplinary management between dermatologists and ophthalmologists is essential in the early diagnosis and management of collagen vascular diseases affecting both the skin and eye. Part I of our series will discuss the ocular manifestations, their diagnosis, and therapeutic options in Sjögren syndrome and systemic lupus erythematosus.

MeSH terms

  • Autoimmune Diseases*
  • Collagen
  • Connective Tissue Diseases*
  • Eyelids
  • Humans
  • Lupus Erythematosus, Systemic* / complications
  • Sjogren's Syndrome* / complications
  • Sjogren's Syndrome* / diagnosis
  • Vascular Diseases*

Substances

  • Collagen