Pronounced QT Prolongation During General Anesthesia in a Child with Left Ventricular Noncompaction Cardiomyopathy: A Case Report

Anesth Prog. 2023 Sep 1;70(3):137-139. doi: 10.2344/anpr-70-02-12.

Abstract

We report the case of an 8-year-old boy with left ventricular noncompaction cardiomyopathy (LVNC) and QT prolongation who experienced further prolongation of the QTc during general anesthesia for extraction of a maxillary mesiodens. Pronounced prolongation of the QTc was observed after induction of general anesthesia with thiamylal and during emergence. No notable fluctuations in blood pressure, heart rate, and estimated continuous cardiac output were observed. We considered it likely that the QT prolongation was triggered by thiamylal and increased sympathetic nervous system activity. During general anesthesia for children with LVNC and QT prolongation, it is necessary to monitor intraoperative hemodynamic fluctuations and prepare for the possible occurrence of arrhythmias.

Keywords: Cardiac output; General anesthesia; Left ventricular noncompaction; QT prolongation; QTc.

Publication types

  • Case Reports

MeSH terms

  • Anesthesia, General / adverse effects
  • Arrhythmias, Cardiac
  • Cardiomyopathies* / complications
  • Cardiomyopathies* / diagnosis
  • Child
  • Electrocardiography / adverse effects
  • Humans
  • Long QT Syndrome* / diagnosis
  • Long QT Syndrome* / etiology
  • Male
  • Thiamylal

Substances

  • Thiamylal