Erysipelothrix rhusiopathiae cellulitis with associated bacteraemia following seafood preparation

BMJ Case Rep. 2023 Oct 17;16(10):e248430. doi: 10.1136/bcr-2021-248430.

Abstract

Erysipelothrix rhusiopathiae is a pleomorphic Gram-positive bacillus, zoonotic pathogen of mammals, birds and fish. Human disease caused by this organism most commonly occurs following occupational or recreational exposure to infected animals and typically presents as a localised cutaneous disease. Invasive infection resulting in bacteraemia, endocarditis or other distant sequelae is infrequently seen. Most commonly, invasive infection is seen in patients with predisposing risk factors including diabetes, immunocompromising conditions, alcohol use disorder or chronic kidney disease. The organism is highly susceptible to penicillin-class drugs which serve as first-line antimicrobial therapy with prolonged courses typically prescribed for invasive disease, given the predilection of this organism to cause endocarditis. In this report, we present an interesting case of a polymicrobial finger abscess with E. rhusiopathiae bacteraemia following laceration with a fish spine in an immunocompetent patient in Southern US state. This bacteraemic episode was successfully treated with a fluoroquinolone course owing to patient's penicillin allergy.

Keywords: Drugs: infectious diseases; Infectious diseases.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia* / complications
  • Bacteremia* / drug therapy
  • Cellulitis / complications
  • Cellulitis / drug therapy
  • Endocarditis* / drug therapy
  • Erysipelothrix Infections* / diagnosis
  • Erysipelothrix Infections* / drug therapy
  • Erysipelothrix*
  • Humans
  • Mammals
  • Penicillins / therapeutic use
  • Seafood / adverse effects

Substances

  • Anti-Bacterial Agents
  • Penicillins