Advances in swept-source optical coherence tomography and optical coherence tomography angiography

Fang Zheng; Xiaofeng Deng; Qi Zhang; Jingliang He; Panpan Ye; Shan Liu; Peng Li; Jian Zhou; Xiaoyun Fang

doi:10.1016/j.aopr.2022.10.005

Advances in swept-source optical coherence tomography and optical coherence tomography angiography

Adv Ophthalmol Pract Res. 2022 Nov 25;3(2):67-79. doi: 10.1016/j.aopr.2022.10.005. eCollection 2023 May-Jun.

Authors

Fang Zheng¹, Xiaofeng Deng², Qi Zhang¹, Jingliang He¹, Panpan Ye¹, Shan Liu³, Peng Li², Jian Zhou⁴, Xiaoyun Fang¹

Affiliations

¹ Eye Center, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
² State Key Lab of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou, China.
³ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁴ TowardPi (Beijing) Medical Technology Ltd, Shanghai, China.

Abstract

Background: The fast development of swept-source optical coherence tomography (SS-OCT) and swept-source optical coherence tomography angiography (SS-OCTA) enables both anterior and posterior imaging of the eye. These techniques have evolved from a research tool to an essential clinical imaging modality.

Main text: The longer wavelength and faster speed of SS-OCT and SS-OCTA facilitate better visualization of structure and vasculature below pigmented tissue with a larger field of view of the posterior segment and 360-degree visualization of the anterior segment. In the past 10 years, algorithms dealing with OCT and OCTA data also vastly improved the image quality and enabled the automated quantification of OCT- and OCTA-derived metrics. This technology has enriched our current understanding of healthy and diseased eyes. Even though the high cost of the systems currently limited the widespread use of SS-OCT and SS-OCTA at the first beginning, the gap between research and clinic practice got obviously shortened in the past few years.

Conclusions: SS-OCT and SS-OCTA will continue to evolve rapidly, contributing to a paradigm shift toward more widespread adoption of new imaging technology in clinical practice.

Keywords: Anterior segment; Posterior segment; Swept-source optical coherence tomography; Swept-source optical coherence tomography angiography; Vitreous.

Publication types

Review