Comparison of efficacy of non-pharmacological intervention for post-stroke dysphagia: a systematic review and Bayesian network meta-analysis

BMC Neurosci. 2023 Oct 16;24(1):53. doi: 10.1186/s12868-023-00825-0.

Abstract

Increasingly, non-pharmacological interventions are being identified and applied to post-stroke dysphagia. Nevertheless, there is insufficient evidence to assess which type of interventions are more effective. In this study, the randomized controlled trials of non-pharmacological interventions on post-stroke dysphagia were retrieved from the relevant databases. Including 96 studies and 12 non-drug treatments. Then, and the network meta-analysis is carried out by statistical software. The results show: In the aspects of videofluoroscopic swallowing study (VFSS), Standardized Swallowing Assessment (SSA), swallowing-quality of life (SWAL-QOL), Water swallow test (WST); Acupuncture + electrotherapy + rehabilitation training, acupuncture + rehabilitation training + massage, electrotherapy + rehabilitation training, acupuncture + electrotherapy + rehabilitation training, electrotherapy, acupuncture + rehabilitation training + acupoints sticking application have significant effects in post-stroke dysphagia. Compared with other interventions, they have more advantages in improving the above indicators. A substantial number of high-quality randomized clinical trials are still necessary in the prospective to validate the therapeutic effectiveness of non-pharmacological interventions in post-stroke dysphagia and the results of this Bayesian network meta-analysis.

Keywords: Bayesian network meta-analysis; Effectiveness; Non-pharmacological intervention; Post-stroke dysphagia.

Publication types

  • Systematic Review
  • Meta-Analysis
  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acupuncture Therapy* / methods
  • Bayes Theorem
  • Deglutition Disorders* / etiology
  • Deglutition Disorders* / therapy
  • Humans
  • Network Meta-Analysis
  • Prospective Studies
  • Quality of Life
  • Randomized Controlled Trials as Topic
  • Stroke* / complications
  • Stroke* / therapy
  • Treatment Outcome