Cell-mediated and humoral immunity parameters were investigated at different dates of myocardial infarction and compared with the blood tests. A diagram is proposed correlating changes of immune status to blood test results, as an instrument for the assessment of changes in immune status on the basis of blood composition. Immunologic changes (defense immunodeficiency and developing cytotoxic component) associated with acute myocardial infarction, and disorders of immunologic control persisting to the time of discharge were demonstrated. Immunologic tests with specific antigens help to decipher the nature of immunity disorders detectable on the basis of blood test results.