End-Organ Damage in Hypertension: An Insight on a Differentiated Outpatient Consultation

Cureus. 2023 Sep 12;15(9):e45105. doi: 10.7759/cureus.45105. eCollection 2023 Sep.

Abstract

Objective: The objective of this study was to determine the prevalence of end-organ damage in hypertensive patients attending an outpatient consultation.

Materials and methods: Patients were selected from an outpatient consultation at a tertiary hospital care center. All patients who consulted between July 2022 and March 2023 were included. Data on demographic characteristics, blood pressure records, hypertension etiology, medication use, and the presence of target organ damage were collected.

Results: A total of 73 patients were included in the study, with 34 patients being male (46.6%) and 39 patients being female (53.4%). The mean age of the patients was 49.8 years. Among the cases of hypertension, 14 (19.2%) were classified as secondary arterial hypertension (AH). The most common cause of secondary AH was obstructive sleep apnea (OSA) (42.9%). Approximately 23.2% of patients had documented end-organ damage potentially related to hypertension, with kidney disease being the most frequent (n = 10, 13.7%). The most commonly prescribed pharmacological classes were angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists (n = 46, 63%).

Conclusion: Despite numerous studies and trials on arterial hypertension, it remains a significant contributor to morbidity and mortality, necessitating the continued awareness of its long-term implications.

Keywords: hypertension; obstructive sleep apnea; public health and safety; renal hypertension; renovascular hypertension.