β-Glucan extracts as high-value multifunctional ingredients for skin health: A review

Carbohydr Polym. 2023 Dec 15:322:121329. doi: 10.1016/j.carbpol.2023.121329. Epub 2023 Aug 23.

Abstract

β-Glucans, which are naturally present in cereals, yeast, and mushrooms, have gained attention as a potential natural source for functional foods and pharmaceuticals. Due to the availability of β-glucans from several sources, different extraction methods can be employed to obtain high purity extracts that can be further modified to enhance their solubility or other biological properties. Apart from their known ability to interact with the immune system, β-glucans possess specific properties that could benefit overall skin health and prevent age-related signs, including soothing and antioxidant activities. As a result, the use of β-glucans to mitigate damage caused by environmental stressors or skin-related issues that accelerate skin aging or trigger chronic inflammation may represent a promising, natural, eco-friendly, and cost-effective approach to maintaining skin homeostasis balance. This review outlines β-glucan extraction methodologies, molecular structure, functionalization approaches, and explores skin-related benefits of β-glucans, along with an overview of related products in the market.

Keywords: Biological properties; Chemical modification; Extraction; Immunomodulation; Skincare; β-Glucans.

Publication types

  • Review

MeSH terms

  • Agaricales* / chemistry
  • Antioxidants / pharmacology
  • Antioxidants / therapeutic use
  • Skin
  • Solubility
  • beta-Glucans* / chemistry
  • beta-Glucans* / therapeutic use

Substances

  • beta-Glucans
  • Antioxidants