The Therapeutic Aryl Hydrocarbon Receptor-Modulating Agent Tapinarof Regulates SEMA3A Expression in Human Keratinocytes through NRF2

J Invest Dermatol. 2024 Mar;144(3):710-713.e8. doi: 10.1016/j.jid.2023.10.002. Epub 2023 Oct 12.
No abstract available

Keywords: Aryl hydrocarbon receptor; Atopic dermatitis; NRF2; SEMA3A; Tapinarof.

MeSH terms

  • Humans
  • Keratinocytes / metabolism
  • NF-E2-Related Factor 2* / genetics
  • NF-E2-Related Factor 2* / metabolism
  • Receptors, Aryl Hydrocarbon / genetics
  • Receptors, Aryl Hydrocarbon / metabolism
  • Resorcinols
  • Semaphorin-3A*
  • Stilbenes*

Substances

  • tapinarof
  • NF-E2-Related Factor 2
  • Semaphorin-3A
  • Receptors, Aryl Hydrocarbon
  • Resorcinols
  • SEMA3A protein, human
  • Stilbenes