Hypoxic microenvironment determines the phenotypic plasticity and spatial distribution of cancer-associated fibroblasts

Jae-Il Choi; Eun Jeong Cho; Min Jae Yang; Hyun-Jin Noh; So Hyun Park; Seokhwi Kim; You-Sun Kim; Chang Ohk Sung; Dakeun Lee

doi:10.1002/ctm2.1438

Hypoxic microenvironment determines the phenotypic plasticity and spatial distribution of cancer-associated fibroblasts

Clin Transl Med. 2023 Oct;13(10):e1438. doi: 10.1002/ctm2.1438.

Authors

Jae-Il Choi^#^{1

2}, Eun Jeong Cho^#^{3

4}, Min Jae Yang⁵, Hyun-Jin Noh^{2

6}, So Hyun Park^{1

2}, Seokhwi Kim^{1

2}, You-Sun Kim^{2

6}, Chang Ohk Sung^{3

4}, Dakeun Lee^{1

2}

Affiliations

¹ Department of Pathology, Ajou University School of Medicine, Suwon, South Korea.
² Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, South Korea.
³ Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
⁴ Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
⁵ Department of Internal Medicine, Ajou University School of Medicine, Suwon, South Korea.
⁶ Department of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, South Korea.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adaptation, Physiological
Cancer-Associated Fibroblasts*
Fibroblasts
Humans
Hypoxia
Neoplasms* / genetics