The correlation between transient osteoporosis of the hip and pregnancy: A review

Medicine (Baltimore). 2023 Oct 13;102(41):e35475. doi: 10.1097/MD.0000000000035475.

Abstract

Transient osteoporosis of the hip is indubitably a comparatively infrequent entity affecting both men and women worldwide. Its occurrence in the course of pregnancy, specifically in the third trimester, and lactation are of paramount concernment. The exact association between transient hip osteoporosis and pregnancy is precarious. Etiology and potential pathophysiological mechanisms behind this correlation are still to be utterly defined. Magnetic resonance imaging is highly regarded as the gold standard imaging method for assiduous assessment of this disorder. Physicians of copious medical specialties should practice scrupulous techniques for early and pertinent diagnosis when pregnant women are presented with persistent hip pain, as differential diagnosis with femoral head avascular necrosis can be exceedingly arduous. Treatment is predominantly conservative with protected weight-bearing and analgesic medication in the first line of management. In terms of prognosis, the disease ordinarily resolves spontaneously after a few months. Further research is required in order to elucidate the ambiguity surrounding the establishment of globally approved diagnosis and treatment guidelines for pregnancy-associated transient hip osteoporosis. This paper aims to accentuate the significance of this particular disorder by providing a succinct review of the existing literature, augmenting clinicians' knowledge about the features of pregnancy-related transient proximal femur osteoporosis.

Publication types

  • Review

MeSH terms

  • Female
  • Hip
  • Hip Joint / pathology
  • Humans
  • Magnetic Resonance Imaging / methods
  • Male
  • Osteoporosis* / complications
  • Osteoporosis* / diagnosis
  • Osteoporosis* / drug therapy
  • Pregnancy
  • Pregnancy Complications* / drug therapy