Can statin preventative treatment inform geroscience-guided therapeutics?

Aging Cell. 2023 Dec;22(12):e13998. doi: 10.1111/acel.13998. Epub 2023 Oct 13.

Giovanni Guaraldi^{1

2}, Kristine M Erlandson³, Jovana Milic^{1

2}, Alan L Landay⁴, Monty A Montano⁵

¹ Modena HIV Metabolic Clinic, University of Modena and Reggio Emilia, Modena, Italy.
² Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.
³ Division of Infectious Diseases, Department of Medicine, University of Colorado-Anshutz Medical Campus, Aurora, Colorado, USA.
⁴ Department of Internal Medicine, Rush University, Chicago, Illinois, USA.
⁵ Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

Abstract

Potential senotherapeutic effect of statins may lead to prevention and reduction of frailty.

Keywords: HIV; geroscience; statin.