An unusual presentation of ossified spinal meningioma: case report and literature review

Wen-Bin Xu; Nai-Kun Sun; Di-Xin Cai; Ding-Qiang Chen; Yuan Niu; Fang Jia; Guang-Xun Lin; Gang Rui

doi:10.3389/fonc.2023.1259508

An unusual presentation of ossified spinal meningioma: case report and literature review

Front Oncol. 2023 Sep 27:13:1259508. doi: 10.3389/fonc.2023.1259508. eCollection 2023.

Authors

Wen-Bin Xu¹, Nai-Kun Sun^{1

2}, Di-Xin Cai^{1

2}, Ding-Qiang Chen², Yuan Niu³, Fang Jia¹, Guang-Xun Lin^{1

2}, Gang Rui^{1

2}

Affiliations

¹ Department of Orthopedics, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
² The Third Clinical Medical College, Fujian Medical University, Fuzhou, China.
³ Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Nanchang, China.

Abstract

Background: Spinal meningioma is a common intraspinal tumor, which mainly occurs in the thoracic spine. Ossified meningioma (OSM) is an extremely rare histological variant. Our article reports a rare patient with dorsal complete OSM and reviews this subject.

Case presentation: A 68-year-old woman presented with a one-year history of progressive weakness in both lower limbs with gait disturbance. Physical examination revealed hypoesthesia with a sensory level below T10. Babinski and pathological signs on both sides were weakly positive. Magnetic resonance imaging (MRI) showed a mass at the T10 to T11 level causing severe compression of the spinal cord. Computed tomography (CT) showed complete ossification of the mass. 18F-Fluoro-deoxy-glucose positron emission tomography CT (18F-FDG PET/CT) scan combined with MRI revealed that the mass was an intradural extramedullary high-density ossified nodule. The patient underwent a gross total resection of the mass and pathologic examination indicated that the mass was a meningioma with diffused psammomatous bodies.

Conclusion: We identified a rare case of dorsal complete OSM occurring in a 68-year-old woman. After complete surgical resection, although there were complications such as cerebral fluid leakage and fever, the patient finally recovered with a satisfactory result.

Keywords: dorsal completely ossified meningioma; literature review; ossification; spinal meningioma; thoracic spine tumor.

Publication types

Review

Grants and funding

The authors declare financial support was received for the research, authorship, and/or publication of this article. This research was funded by the Natural Science Foundation of Fujian Province (No. 2020J011244) and the "Xiamen Health System Discipline Leaders and their Backup Candi-dates, Senior Management Talent Training Candidates Training Program (2021)".