2023 Korean Endocrine Society Consensus Guidelines for the Diagnosis and Management of Primary Aldosteronism

Endocrinol Metab (Seoul). 2023 Dec;38(6):597-618. doi: 10.3803/EnM.2023.1789. Epub 2023 Oct 13.

Abstract

Primary aldosteronism (PA) is a common, yet underdiagnosed cause of secondary hypertension. It is characterized by an overproduction of aldosterone, leading to hypertension and/or hypokalemia. Despite affecting between 5.9% and 34% of patients with hypertension, PA is frequently missed due to a lack of clinical awareness and systematic screening, which can result in significant cardiovascular complications. To address this, medical societies have developed clinical practice guidelines to improve the management of hypertension and PA. The Korean Endocrine Society, drawing on a wealth of research, has formulated new guidelines for PA. A task force has been established to prepare PA guidelines, which encompass epidemiology, pathophysiology, clinical presentation, diagnosis, treatment, and follow-up care. The Korean clinical guidelines for PA aim to deliver an evidence-based protocol for PA diagnosis, treatment, and patient monitoring. These guidelines are anticipated to ease the burden of this potentially curable condition.

Keywords: Diagnosis; Guideline; Hypertension; Primary aldosteronism; Treatment.

MeSH terms

  • Aldosterone
  • Humans
  • Hyperaldosteronism* / diagnosis
  • Hyperaldosteronism* / therapy
  • Hypertension* / diagnosis
  • Hypertension* / etiology
  • Hypertension* / therapy
  • Mineralocorticoid Receptor Antagonists / therapeutic use
  • Republic of Korea / epidemiology

Substances

  • Aldosterone
  • Mineralocorticoid Receptor Antagonists