An overview on state-of-art of micromixer designs, characteristics and applications

Xin Wang; Zhanqiang Liu; Bing Wang; Yukui Cai; Qinghua Song

doi:10.1016/j.aca.2023.341685

An overview on state-of-art of micromixer designs, characteristics and applications

Anal Chim Acta. 2023 Oct 23:1279:341685. doi: 10.1016/j.aca.2023.341685. Epub 2023 Aug 2.

Authors

Xin Wang¹, Zhanqiang Liu², Bing Wang¹, Yukui Cai¹, Qinghua Song¹

Affiliations

¹ School of Mechanical Engineering, Shandong University, Jinan 250061, Shandong, China; Key Laboratory of High Efficiency and Clean Mechanical Manufacture of MOE/Key National Demonstration Center for Experimental Mechanical Engineering Education, Jinan 250061, Shandong, China.
² School of Mechanical Engineering, Shandong University, Jinan 250061, Shandong, China; Key Laboratory of High Efficiency and Clean Mechanical Manufacture of MOE/Key National Demonstration Center for Experimental Mechanical Engineering Education, Jinan 250061, Shandong, China. Electronic address: melius@sdu.edu.cn.

PMID: 37827660
DOI: 10.1016/j.aca.2023.341685

Abstract

Micromixers are characterized based on characteristics such as excellent mixing efficiency, low reagent cost and flexible controllability compared with conventional reactors in terms of macro size. A variety of designs and applications of micromixers have been proposed. The focus of current reviews is restricted to micromixer structures. Each type of micromixer has characteristics corresponding to its structure, which determines the suitable application areas. This paper provides an overview connecting micromixer designs and their applications. First, the typical designs and mixing mechanisms of both passive and active micromixers are summarized. Then, application cases of micromixers, including chemical, biological and medical applications, are presented. The characteristics, including the advantages and restrictions of different micromixers, are discussed. Finally, the future perspective of micromixer design is proposed. It is predictable that micromixers will have widespread applications by integrating two or more different mixing methods together. This review would be beneficial to guide the design of micromixers applied for specific purposes.

Keywords: Active micromixer; Applications; Characteristics; Passive micromixer; Structure design.

Publication types

Review