A specialized Y-type pipeline is developed to replace medical disposable Y-type pipelines for ventilator calibration and to improve accuracy, providing a reference for improvement. According to the calibration specifications of ventilators, tests are performed on specialized pipelines and more to compare their data. Taking the tidal volume 400-mL detection point as an example, the calibration errors made by medical disposable pipelines and specialized pipelines are 6.2% and -0.8%, respectively, and the errors at other detection points are roughly the same. The accuracy of the specialized Y-type pipeline has significantly improved, reducing the impact of the pipeline on tidal volume calibration from more than 6% to less than 1%. The use of specialized pipelines can significantly improve the accuracy and qualification rate of calibration, reducing the consumption of disposable Y-type pipelines and thereby significantly reducing costs and increasing efficiency.