Tracheobronchitis and laryngitis associated with Crohn's disease

Shogo Nakai; Moeko Morikawa; Toshiya Hiramatsu; Yurina Murakami; Koji Nishimoto; Sayomi Matsushima; Masanori Harada; Tomohiro Uto; Jun Sato; Shiro Imokawa; Takafumi Suda

doi:10.1016/j.rmcr.2023.101918

Tracheobronchitis and laryngitis associated with Crohn's disease

Respir Med Case Rep. 2023 Sep 26:46:101918. doi: 10.1016/j.rmcr.2023.101918. eCollection 2023.

Authors

Affiliations

¹ Division of Respiratory Medicine, Iwata City Hospital, 512-3, Ookubo, Iwata, Shizuoka, 438-8550, Japan.
² Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-ku, Hamamatus, 431-3192, Japan.

Abstract

We report a 68-year-old woman with tracheobronchitis and laryngitis associated with Crohn's disease (CD), which was discovered during the evaluation of suspected lung cancer. She had no symptoms induced by these upper airway diseases (UADs). Bronchoscopy revealed swelling of the epiglottis with edematous change and a mass like epiglottis fold. There were nodular and edematous changes in the trachea and bilateral main bronchus. Histological findings demonstrated infiltration by numerous lymphocytes and plasma cells. Dexamethasone as the premedication for chemotherapy against lung cancer was efficacious for these extraintestinal manifestations of CD. Our case was rare in that bronchial lesion and UADs appeared concomitantly.

Keywords: Bronchoscopy; Cobble stone appearance; Inflammatory bowel disease; Tracheobronchial involvement.

Publication types

Case Reports