Influenza Vaccine Effectiveness Against Influenza-Associated Hospitalization in Hong Kong Children Aged 9 Months to 17 Years, March-June 2023

Benjamin J Cowling; Mike Y W Kwan; Caitriona Murphy; Eunice L Y Chan; Joshua S C Wong; Sheena G Sullivan; Malik Peiris; So-Lun Lee

doi:10.1093/jpids/piad083

Influenza Vaccine Effectiveness Against Influenza-Associated Hospitalization in Hong Kong Children Aged 9 Months to 17 Years, March-June 2023

J Pediatric Infect Dis Soc. 2023 Nov 30;12(11):586-589. doi: 10.1093/jpids/piad083.

Authors

Benjamin J Cowling^{1

2}, Mike Y W Kwan³, Caitriona Murphy¹, Eunice L Y Chan⁴, Joshua S C Wong³, Sheena G Sullivan^{5

6}, Malik Peiris^{1

7}, So-Lun Lee^{4

8}

Affiliations

¹ WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
² Laboratory of Data Discovery for Health Limited, Hong Kong Science and Technology Park, New Territories, Hong Kong Special Administrative Region, China.
³ Department of Paediatrics and Adolescent Medicine, Princess Margaret Hospital, Hong Kong Special Administrative Region, China.
⁴ Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
⁵ WHO Collaborating Centre for Reference and Research on Influenza, Royal Melbourne Hospital, and Department of Infectious Diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
⁶ Department of Epidemiology, University of California, Los Angeles, California, USA.
⁷ Centre for Immunology & Infection, Hong Kong Science and Technology Park, New Territories, Hong Kong Special Administrative Region, China.
⁸ Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Hong Kong Special Administrative Region, China.

PMID: 37818976
PMCID: PMC10687596 (available on 2024-10-11)
DOI: 10.1093/jpids/piad083

Abstract

In March-June 2023, we conducted a test-negative study in 1671 children who were hospitalized with acute respiratory illness in Hong Kong. Two hundred and eighty-six children (17.2%) were tested positive for influenza virus including 188 with A(H1N1). We estimated influenza vaccine effectiveness against influenza-associated hospitalization as 69.6% (95% confidence interval: 49.3%, 81.7%).

Keywords: influenza; vaccination; vaccine effectiveness.

© The Author(s) 2023. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

MeSH terms

Child
Hong Kong / epidemiology
Hospitalization
Humans
Influenza A Virus, H1N1 Subtype*
Influenza Vaccines* / therapeutic use
Influenza, Human* / epidemiology
Influenza, Human* / prevention & control
Seasons
Vaccination
Vaccine Efficacy

Substances

Influenza Vaccines

Abstract

MeSH terms

Substances

Grants and funding