The 1st IEEE Engineering in Medicine and Biology Society (EMBS) and the University of Pécs International Conference on Biomedical Engineering and Innovation (ICBEI) was held on 24-26 October 2022, in Pécs, Hungary. The conference opened with welcome talks by Prof. Attila Miseta, the rector of the University of Pécs (UP), Prof. Miklos Nyitrai, the dean of the UP, and Prof. Metin Akay, the president of IEEE EMBS, who delivered the first keynote talk at the conference. Then, we enjoyed three more exceptional keynote talks by Dr. Yasemin Akay, Dr. Gabor Forgacs, and Dr. Istvan Ulbert (Figure 1). With the participation of 230+ people, nine keynote lectures, and nine health care companies holding exhibitions, the conference was exceptional and well organized by Dr. Luca Toth, Dr. Adam Schiffer, and Dr. Peter Maroti, M.D., Ph.D., from the Centre for Biomedical Engineering and Innovation (Figure 2). The conference organizing team did a fantastic job. The attendance by several medical school students, the participation of health care companies (Figure 3), the hackathon competition, and several workshops were the highlights of the event. The first day of the conference concluded with a special wine tasting sponsored by the University of Pécs Wine Research Institute. Then, the conference organizing committee appreciation dinner hosted by Luca Tóth, Adam Schiffer, and Péter Maróti in the historical city of Pécs was indeed an exceptional social and cultural event (Figure 4).