Emerging applications of machine learning in genomic medicine and healthcare

Crit Rev Clin Lab Sci. 2024 Mar;61(2):140-163. doi: 10.1080/10408363.2023.2259466. Epub 2023 Oct 10.

Abstract

The integration of artificial intelligence technologies has propelled the progress of clinical and genomic medicine in recent years. The significant increase in computing power has facilitated the ability of artificial intelligence models to analyze and extract features from extensive medical data and images, thereby contributing to the advancement of intelligent diagnostic tools. Artificial intelligence (AI) models have been utilized in the field of personalized medicine to integrate clinical data and genomic information of patients. This integration allows for the identification of customized treatment recommendations, ultimately leading to enhanced patient outcomes. Notwithstanding the notable advancements, the application of artificial intelligence (AI) in the field of medicine is impeded by various obstacles such as the limited availability of clinical and genomic data, the diversity of datasets, ethical implications, and the inconclusive interpretation of AI models' results. In this review, a comprehensive evaluation of multiple machine learning algorithms utilized in the fields of clinical and genomic medicine is conducted. Furthermore, we present an overview of the implementation of artificial intelligence (AI) in the fields of clinical medicine, drug discovery, and genomic medicine. Finally, a number of constraints pertaining to the implementation of artificial intelligence within the healthcare industry are examined.

Keywords: Genomic medicine; artificial intelligence; clinical medicine; deep learning; machine learning.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Artificial Intelligence*
  • Delivery of Health Care
  • Genomic Medicine*
  • Humans
  • Machine Learning