Use of Peroral Pancreatoscopy in the Diagnosis of Elusive Intraductal Papillary Mucinous Neoplasm With High-Grade Dysplasia

Mabel Angela T Sarita; Arata Sakai; Masahiro Tsujimae; Takashi Kobayashi; Atsuhiro Masuda; Maki Kanzawa; Hirochika Toyama; Yuzo Kodama

doi:10.14309/crj.0000000000001165

Use of Peroral Pancreatoscopy in the Diagnosis of Elusive Intraductal Papillary Mucinous Neoplasm With High-Grade Dysplasia

ACG Case Rep J. 2023 Oct 5;10(10):e01165. doi: 10.14309/crj.0000000000001165. eCollection 2023 Oct.

Authors

Mabel Angela T Sarita^{1

2}, Arata Sakai¹, Masahiro Tsujimae¹, Takashi Kobayashi¹, Atsuhiro Masuda¹, Maki Kanzawa³, Hirochika Toyama⁴, Yuzo Kodama¹

Affiliations

¹ Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
² Institute of Digestive and Liver Diseases, St. Luke's Medical Center, Quezon City, Philippines.
³ Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan.
⁴ Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Abstract

Intraductal papillary mucinous neoplasm (IPMN) is a premalignant lesion of the pancreas that can occasionally manifest as recurrent acute pancreatitis. In this report, we discuss a unique case of a 49-year-old woman who presented with recurrent acute pancreatitis of an unknown cause for several years. Workup using peroral pancreatoscopy eventually showed main-duct IPMN with high-grade dysplasia as the obscure cause of recurrent acute pancreatitis. This case report highlights the clinical course of main-duct IPMN and the evolving role of peroral pancreatoscopy in patients with recurrent acute pancreatitis.

Keywords: intraductal papillary mucinous neoplasm; peroral pancreatoscopy; recurrent acute pancreatitis.

Publication types

Case Reports