Prominin-1 expression in the testis/epididymis and fertility

Christine A Fargeas; József Jászai; Denis Corbeil

doi:10.1002/rmb2.12544

Prominin-1 expression in the testis/epididymis and fertility

Reprod Med Biol. 2023 Oct 4;22(1):e12544. doi: 10.1002/rmb2.12544. eCollection 2023 Jan-Dec.

Authors

Christine A Fargeas¹, József Jászai², Denis Corbeil¹

Affiliations

¹ Tissue Engineering Laboratories, Biotechnology Center (BIOTEC) Center for Molecular and Cellular Bioengineering and Medizinische Fakultät der Technischen Universität Dresden Dresden Germany.
² Institute of Anatomy Medizinische Fakultät der Technischen Universität Dresden Dresden Germany.

Abstract

The contribution of Prominin-1 (aka CD133) to male fertility has recently been (re)investigated, with contradictory results. Early findings, essential for deciphering its role, have unfortunately been neglected. Here, the authors present what is currently known about its expression in the male reproductive system of rodents and men so that its involvement in male fertility can be re-examined and discussed in the light of these elements.

Keywords: CD133; prominin‐1; reproductive system; sperm cell.

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