Proposal of a New Conformal Factor and Normal Tissue Penalty Factor for Radiosurgery Treatments

Cureus. 2023 Sep 6;15(9):e44800. doi: 10.7759/cureus.44800. eCollection 2023 Sep.

Abstract

The quality of a treatment plan is evaluated by the conformality of the prescribed isodose around the target and the homogeneity of dose distribution inside the target. Presently, to check the target volume conformality, a number of published conformity indices are in use. Most of these indices are based on the target volume coverage by prescribed isodose, with respect to the total volume of the target. Some take into account the normal tissue covered by the prescribed isodose and suitably weigh the target coverage to evaluate conformity. In this study, for the irradiation of normal tissue by the prescription isodose, a normal tissue penalty factor is proposed and for the target conformality, a new conformal factor is proposed by applying this normal tissue penalty factor to the target coverage. The proposed conformal factor is evaluated for a few sample analytical cases and the results are compared with those obtained using the published conformity indices.

Keywords: ci; conf; normal tissue; ntpf; reference isodose; target volume.