Emerging programmable nuclease-based detection for food safety

Yaru Li; Jingyu Jia; Shuli Man; Shengying Ye; Long Ma

doi:10.1016/j.tibtech.2023.09.006

Emerging programmable nuclease-based detection for food safety

Trends Biotechnol. 2024 Feb;42(2):151-155. doi: 10.1016/j.tibtech.2023.09.006. Epub 2023 Oct 7.

Authors

Yaru Li¹, Jingyu Jia¹, Shuli Man², Shengying Ye³, Long Ma⁴

Affiliations

¹ Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China; State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China; Tianjin Key Laboratory of Industry Microbiology, National and Local United Engineering Lab of Metabolic Control Fermentation Technology, Tianjin, 300457, China; College of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China.
² Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China; State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China; Tianjin Key Laboratory of Industry Microbiology, National and Local United Engineering Lab of Metabolic Control Fermentation Technology, Tianjin, 300457, China; College of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China. Electronic address: msl@tust.edu.cnm.
³ Pharmacy Department, The 983th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Tianjin, 300142, China. Electronic address: jbskxb@163.com.
⁴ Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China; State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China; Tianjin Key Laboratory of Industry Microbiology, National and Local United Engineering Lab of Metabolic Control Fermentation Technology, Tianjin, 300457, China; College of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China. Electronic address: malong@tust.edu.cn.

PMID: 37806898
DOI: 10.1016/j.tibtech.2023.09.006

Abstract

Food safety issues are an important challenge across the world. Programmable nucleases are emerging as new tools because of their significant biological advantages. This forum article provides an overview of recent advances and challenges in the novel paradigm of programmable nuclease-based detection for food safety.

Keywords: Argonaute; CRISPR/Cas; food safety detection; programmable nuclease.

MeSH terms

CRISPR-Cas Systems*
Endonucleases* / genetics
Food Safety

Substances

Endonucleases