At present, effective reconstruction of the integrity and functionality of damaged skin tissue remains an important medical problem in the field of wound repair. In recent years, the rapid development of nanozymes and tissue engineering scaffolds in the field of regenerative medicine has made it possible to develop new skin wound repair materials. Based on the process of skin wound repair and regeneration, this review briefly describes the nanozymes and its catalytic mechanism. At the same time, the common tissue engineering scaffolds loaded with nanozymes and their manufacturing strategies are introduced, the application of tissue engineering scaffolds loaded with nanozymes during the stages of anti-bacteria and anti-inflammation in the process of wound repair is summarized, and their future development direction is discussed.
有效重建受损皮肤组织并恢复其完整性和功能性仍是当前创伤修复领域面临的重要医学问题。近年来，纳米酶和组织工程支架在再生医学领域的飞速发展，使得开发新型皮肤创伤修复材料成为可能。该综述立足于皮肤创伤修复与再生过程，简述了纳米酶及其催化机制，同时介绍了常见的负载纳米酶的组织工程支架及其制造策略，总结了负载纳米酶的组织工程支架在创面修复过程中抗菌、抗炎等阶段的应用并探讨了其未来发展方向。.