Swine global genomic resources: insights into wild and domesticated populations

Mamm Genome. 2023 Dec;34(4):520-530. doi: 10.1007/s00335-023-10012-5. Epub 2023 Oct 7.

Abstract

Suids, both domesticated and wild, are found on all continents except for Antarctica and provide valuable food resources for humans in addition to serving as important models for biomedical research. Continuing advances in genome sequencing have allowed researchers to compare the genomes from diverse populations of suids helping to clarify their evolution and dispersal. Further analysis of these samples may provide clues to improve disease resistance/resilience and productivity in domestic suids as well as better ways of classifying and conserving genetic diversity within wild and captive suids. Collecting samples from diverse populations of suids is resource intensive and may negatively impact endangered populations. Here we catalog extensive tissue and DNA samples from suids in collections in both Europe and North America. We include samples that have previously been used for whole genome sequencing, targeted DNA sequencing, RNA sequencing, and reduced representation bisulfite sequencing (RRBS). This work provides an important centralized resource for researchers who wish to access published databases.

MeSH terms

  • Animals
  • DNA
  • Genome* / genetics
  • Genomics*
  • Humans
  • Sequence Analysis, DNA
  • Swine
  • Whole Genome Sequencing

Substances

  • DNA