Taking the bait: Strychnine poisoning

Am J Emerg Med. 2023 Dec:74:197.e5-197.e7. doi: 10.1016/j.ajem.2023.09.055. Epub 2023 Oct 2.

Abstract

A 48-year-old male intentionally ingested "gopher killer" containing strychnine as a, suicide attempt. He rapidly developed generalized muscle spasms with opisthotonos followed by cardiovascular collapse. He was resuscitated, treated with 24 h of, neuromuscular paralysis, and was discharged on hospital day 10 without sequelae. A blood strychnine concentration obtained five hours post ingestion was 2.2 mg/L. Strychnine poisoning is exceedingly rare in the modern United States and this report contains a video recording of the classic exam findings.

Keywords: Gopher poison; Opisthotonos; Risus Sardonicus; Strychnine; Toxicology; Trismus.

Publication types

  • Case Reports

MeSH terms

  • Disease Progression
  • Humans
  • Male
  • Middle Aged
  • Poisoning* / therapy
  • Spasm
  • Strychnine*
  • Suicide, Attempted
  • United States

Substances

  • Strychnine