Prioritized regional management for antibiotics and heavy metals in animal manure across China

Abstract

High levels of antibiotics and heavy metals in animal manure pose a potential threat to both the ecological environment and public health. A regional knowledge of their distribution and risk assessment across China remains unclear. A dataset containing 4082 records covering a total of forty-two antibiotics and eight heavy metals was established for animal manure across China. The results showed that the residual concentration of antibiotics was in the order of tetracyclines > aminoglycosides > fluoroquinolones > macrolides > sulfonamides > β-lactams, and that of heavy metals is Zn > Cu > Cr > Pb > Ni > As > Cd > Hg. The mean concentration of antibiotics and heavy metals was higher in pig manure compared to chicken and cow manure (Kruskal-Wallis test). The lowest level of antibiotics was observed in Northwest China based on geographic distribution characteristics. It was related to the high ratio of cow and sheep farming that less antibiotics were administered to. The pollution status of heavy metals was more severe in East China. Furthermore, high correlations were observed between antibiotics (tetracyclines) and heavy metals (Cu, Zn, and As). Especially, tetracycline in North China and Cd in Northeast China exhibited a high risk in manure; thus, they were priority regions for antibiotics/heavy metals pollution control. This study identified risk assessment of typical antibiotics and heavy metals in animal manure and emphasized the necessity of regional management across China.

Keywords: Animal manure; Combined pollution; Risk assessment.