Exercise and Atrial Fibrillation: The Dose Makes the Poison? A Narrative Review

Int J Sports Med. 2024 Jan;45(1):17-22. doi: 10.1055/a-2152-7628. Epub 2023 Oct 6.

Abstract

"All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison" (Paracelsus, ~ 1538 AD). This well-known quote seems to aptly summarize the current understanding of the interaction between exercise and atrial fibrillation (AF). A host of data strongly suggests that regular exercise has a protective effect against developing AF. A small but well-conducted group of trials also demonstrates beneficial effects of exercise in the treatment of AF. Recently, however, potentially detrimental effects of large volumes of high-intensity exercise on the probability of developing AF have moved into the sports-cardiological focus. This effect is well documented for elite athletes; data regarding the general population is less clear. This review presents the current data regarding the protective, therapeutic and potentially risk-enhancing effects of exercise regarding AF. The authors demonstrate that the benefits are clear and strongly outweigh the potential disadvantages.

Publication types

  • Review

MeSH terms

  • Athletes
  • Atrial Fibrillation* / epidemiology
  • Atrial Fibrillation* / prevention & control
  • Exercise
  • Humans
  • Poisons*
  • Sports*

Substances

  • Poisons