The Role of Prohibitin-2 in Diseases

Fang Liu; You Zhang; Zhiyong Guo; An-Jing Ren

doi:10.31083/j.fbl2809211

The Role of Prohibitin-2 in Diseases

Front Biosci (Landmark Ed). 2023 Sep 22;28(9):211. doi: 10.31083/j.fbl2809211.

Authors

Fang Liu¹, You Zhang², Zhiyong Guo², An-Jing Ren¹

Affiliations

¹ Experimental Teaching Center, College of Basic Medical Sciences, Naval Medical University, 200433 Shanghai, China.
² Department of Nephrology, Changhai Hospital, Naval Medical University, 200433 Shanghai, China.

PMID: 37796696
DOI: 10.31083/j.fbl2809211

Abstract

Prohibitin-2 (PHB2) is a conserved protein in mitochondria that regulates various biological processes, including cell cycle, proliferation, apoptosis, transcription, signal transduction, and mitochondrial ridge morphogenesis. Recently, there has been growing interest in the biological function of PHB2. This article primarily discusses the recent advances in the role of PHB2 in diseases.

Keywords: autophagy; diseases; mitochondria; prohibitin-2.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Mitochondria* / genetics
Mitochondria* / metabolism
Prohibitins*
Signal Transduction

Substances

Prohibitins