Acute Appendicitis Complicated by Septic Thrombophlebitis of the Portal Vein Shown by 18 F-FDG and 68 Ga-FAPI-46 PET/CT

Clin Nucl Med. 2023 Nov 1;48(11):997-999. doi: 10.1097/RLU.0000000000004830. Epub 2023 Sep 18.

Abstract

Septic thrombophlebitis of the portal vein is a serious infectious disorder and is difficult to be diagnosed at an early stage. In this case, we presented 18 F-FDG and 68 Ga-FAPI-46 PET/CT findings in a 45-year-old man with acute appendicitis complicated by septic thrombophlebitis of the portal vein. 68 Ga-FAPI-46 PET/CT showed intense radiotracer uptake in the thrombosis of the portal vein, with higher SUV max and larger disease extent than 18 F-FDG PET/CT. This case demonstrated that 68 Ga-FAPI PET/CT may be a useful imaging modality for the diagnosis of this infectious condition.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Appendicitis* / complications
  • Appendicitis* / diagnostic imaging
  • Fluorodeoxyglucose F18
  • Gallium Radioisotopes
  • Humans
  • Male
  • Middle Aged
  • Portal Vein / diagnostic imaging
  • Positron Emission Tomography Computed Tomography
  • Soft Tissue Infections*
  • Thrombophlebitis* / complications
  • Thrombophlebitis* / diagnostic imaging

Substances

  • Fluorodeoxyglucose F18
  • FAPI-46
  • Gallium-68
  • Gallium Radioisotopes