Pre-Workout-Induced Pancreatitis

Cureus. 2023 Sep 3;15(9):e44609. doi: 10.7759/cureus.44609. eCollection 2023 Sep.

Abstract

The use of dietary supplements, including pre-workout formulations, has gained widespread popularity among individuals engaged in sports and fitness. This case report presents a unique instance of pre-workout-induced pancreatitis in a previously healthy young adult. The patient, a 35-year-old male, presented to the emergency department with abdominal pain, elevated pancreatic enzymes, and characteristic radiological findings indicative of acute pancreatitis. The patient's history revealed no prior predisposing factors for pancreatitis such as alcohol consumption or gallstone disease. Extensive diagnostic evaluation excluded other potential causes leading to the suspicion of his pre-workout supplement as the source. Pre-workout supplements contain a blend of stimulants, amino acids, and other metabolic ingredients designed to enhance exercise and muscle performance. Research shows that some of these ingredients, such as amino acids, induce metabolic chain reactions which may damage pancreatic cells. However, there is extremely limited literature regarding these amino acids in combination such as in workout supplements. This case prompts an examination of the potential adverse effects of pre-workout supplements, highlighting the need for increased vigilance among healthcare providers and consumers alike. As the use of these products grows, further research is warranted to allow for safe commercial distribution and to protect consumers from serious harm.

Keywords: acute pancreatitis; adult gastroenterology; amino acid; exercise training; high intensity workout; nutritional supplements; pancreas imaging; physical fitness; pre-workout supplement; sports activities.

Publication types

  • Case Reports