Dismantling silos: The case for an integrated approach to address childhood determinants of lifelong brain health

Ravikiran M Raju; Li-Huei Tsai

doi:10.1016/j.neuron.2023.09.003

Dismantling silos: The case for an integrated approach to address childhood determinants of lifelong brain health

Neuron. 2023 Dec 6;111(23):3706-3709. doi: 10.1016/j.neuron.2023.09.003. Epub 2023 Oct 3.

Authors

Ravikiran M Raju¹, Li-Huei Tsai²

Affiliations

¹ Division of Newborn Medicine, Harvard Medical School, Boston Children's Hospital, Boston, MA, USA; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: rraju@mit.edu.
² Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA.

PMID: 37794591
DOI: 10.1016/j.neuron.2023.09.003

Abstract

Early-life environments have an immense influence on long-term health outcomes. We have started to elucidate the mechanisms underlying this association but have made little progress in reducing the disease burden of environmentally mediated neurological and psychiatric illness. Here, we highlight barriers to innovation and how they may be overcome.

MeSH terms

Brain
Child
Humans
Mental Disorders*