Dermatophyte resistance - on the rise

J Foot Ankle Res. 2023 Oct 5;16(1):69. doi: 10.1186/s13047-023-00665-5.

Abstract

Dermatophytes are group of filamentous fungi which have adapted to living on the skin of humans and other animals. In the last decade, reports have emerged from Asia of new dermatophyte strains showing resistance to the commonly used antifungal agent terbinafine and others. The spread of these resistant strains has been noted in many other countries globally. Little is known about the mechanisms or management of this emerging problem. Urgent research and changes to current practice are required if the spread of the infection is to be contained and managed effectively.

Keywords: Dermatophyte; Drug resistance; Infection; Terbinafine.

Publication types

  • Letter

MeSH terms

  • Animals
  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use
  • Arthrodermataceae*
  • Humans
  • Microbial Sensitivity Tests
  • Naphthalenes
  • Terbinafine

Substances

  • Naphthalenes
  • Antifungal Agents
  • Terbinafine