Silicon parts can contain micrometer-sized vertical cracks that are challenging to detect. Inspection using high-frequency focused ultrasound has shown promise for detecting defects of this size and geometry. However, implementing focused ultrasound to inspect anisotropic media can prove challenging, given the directional dependence of wave propagation and subsequent focusing behavior. In this work, back surface-breaking defects at various orientations within silicon wafers (0°, 15°, and 45° relative to the [010] crystallographic axis) are experimentally inspected in an immersion tank setup. Using 100 MHz unfocused and focused shear waves, the impact of medium anisotropy on focusing and defect detection is evaluated. The scattering amplitude and defect detection sensitivity results demonstrate orientation-dependent patterns that strongly rely on the use of focused transducers. The defects along the 45° orientation reveal two-lobe scattering patterns with maximum amplitudes less than half that of the defects in the 0° orientation, which in contrast show a one-lobe scattering pattern. The experimental results are further explored using finite element (FE) modeling and ray tracing to visualize the impact of focusing on wave propagation within the silicon. Ray tracing results show that the focused beam profiles for the 45° and 0° orientations form a butterfly wing and elliptical focusing profile, respectively, which correspond directly to experimentally found scattering patterns from defects. Additionally, the FE scattering results from unfocused transducers reveal single lobe scattering for both 0° and 45° orientations, proving the varying scattering patterns to be driven by the anisotropic focusing behavior.