Research progress of cancer cell membrane coated nanoparticles for the diagnosis and therapy of breast cancer

Zixia Zhou; Shengmin Zhang; Nianyu Xue

doi:10.3389/fonc.2023.1270407

Research progress of cancer cell membrane coated nanoparticles for the diagnosis and therapy of breast cancer

Front Oncol. 2023 Sep 14:13:1270407. doi: 10.3389/fonc.2023.1270407. eCollection 2023.

Authors

Zixia Zhou¹, Shengmin Zhang¹, Nianyu Xue¹

Affiliation

¹ Department of Ultrasound Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, China.

Abstract

Nanoparticles (NPs) disguised in the cell membrane are a new type of biomimetic platform. Due to their ability to simulate the unique biological functions of membrane-derived cells, they have become one of the hotspots of research at home and abroad. The tumor-specific antigen antibody carried by breast cancer cell membranes can modify nanoparticles to have homologous tumor targeting. Therefore, nanoparticles wrapped in cancer cell membranes have been widely used in research on the diagnosis and treatment of breast cancer. This article reviews the current situation, prospects, advantages and limitations of nanoparticles modified by cancer cell membranes in the treatment and diagnosis of breast cancer.

Keywords: breast cancer; cancer cell membrane coated; molecular imaging; nanoparticles; theragnostic.

Publication types

Review

Grants and funding

The authors declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Natural Science Foundation of Zhejiang Provincial (Project no. BY23H180018) and Medical and Health Technology of Zhejiang Provincial (Project no. 2023KY1065).