Multifunctional role of zinc in human health: an update

EXCLI J. 2023 Aug 4:22:809-827. doi: 10.17179/excli2023-6335. eCollection 2023.

Abstract

Zinc is a multipurpose trace element for the human body, as it plays a crucial part in various physiological processes, such as cell growth and development, metabolism, cognitive, reproductive, and immune system function. Its significance in human health is widely acknowledged, and this has led the scientific community towards more research that aims to uncover all of its beneficial properties, especially when compared to other essential metal ions. One notable area where zinc has shown beneficial effects is in the prevention and treatment of various diseases, including cancer. This review aims to explain the involvement of zinc in specific health conditions such as cancer, coronavirus disease 2019 (COVID-19) and neurological disorders like Alzheimer's disease, as well as its impact on the gut microbiome.

Keywords: Alzheimer's disease; aging; cancer; gut microbiome; immune system; severe acute respiratory syndrome coronavirus 2; zinc.

Publication types

  • Review