1 Prevention of Organ Failure (PROOF) Centre of Excellence, Vancouver, BC, Canada; Centre for Heart Lung Innovation, Providence Research, St Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada; Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
2 Prevention of Organ Failure (PROOF) Centre of Excellence, Vancouver, BC, Canada; Centre for Heart Lung Innovation, Providence Research, St Paul's Hospital, Vancouver, BC V6Z 1Y6, Canada; Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada. Electronic address: scott.tebbutt@hli.ubc.ca.