Complete surgical myocardial revascularization in patients with declined renal functions: 12-month outcomes

BMC Cardiovasc Disord. 2023 Sep 29;23(1):484. doi: 10.1186/s12872-023-03507-1.

Abstract

Introduction: This retrospective observational study aimed to evaluate the feasibility and effectiveness of complete revascularization coronary artery bypass grafting (CABG) in patients with multi-vessel disease (MVD)-CAD and declined renal functions, addressing the knowledge gap regarding optimal treatment strategies and outcomes in this specific patient population.

Methods: Between 2020 and 2022, a total of 58 patients underwent on-pump coronary artery bypass grafting surgery for complete myocardial revascularization in this study. To assess overall survival, Kaplan-Meier with the log-rank test was conducted for statistical analysis.

Results: The mean age of cohort was 60.7. The findings showed a high prevalence of medical conditions such as hypertension (50.0%), diabetes (50.0%), and anaemia (41.4%) among the participants. Intraoperatively, low cardiac output syndrome was reported in 5.2% of cases, while perioperative outcomes indicated a need for transfusions in 53.5% of cases and an in-hospital mortality rate of 3.4%. At the 12-month follow-up, no redo revascularization or renal replacement therapy was required, but cardiac mortality was 5.2% and all-cause mortality was 6.9%.

Conclusions: The study concluded that complete revascularization is safe for these patients and highlights the potential benefits, emphasizing the need for further research in optimizing revascularization techniques for this population.

Keywords: Cardiopulmonary bypass; Coronary artery bypass grafting; Kidney functions.

Publication types

  • Observational Study

MeSH terms

  • Coronary Artery Bypass
  • Coronary Artery Disease* / diagnostic imaging
  • Coronary Artery Disease* / surgery
  • Humans
  • Hypertension* / surgery
  • Kidney / physiology
  • Myocardial Revascularization / adverse effects
  • Reoperation
  • Retrospective Studies
  • Treatment Outcome