A case of complex hemangioendothelioma of the liver in an infant

Rev Esp Enferm Dig. 2023 Nov;115(11):668-670. doi: 10.17235/reed.2023.9949/2023.

Abstract

A physical examination of a 9-month-old female infant presenting with vomiting and diarrhea revealed tenderness in the right upper abdomen and heightened abdominal muscle tone. Abdominal ultrasonography identified an irregular hypoechoic area within the right lobe of the liver. While a subsequent enhanced CT examination disclosed a well-defined lesion exhibiting internal focal calcification and delayed heterogeneous enhancement. Subsequently, she underwent surgical resection, and postoperative pathology revealed areas of epithelioid hemangioendothelioma and cavernous hemangioma. Immunohistochemistry demonstrated positive expression of CD34, CD31, FLI-1, and F-VIII. The pathologic diagnosis was confirmed as composite hemangioendothelioma (CHE).

Publication types

  • Case Reports

MeSH terms

  • Abdomen
  • Antigens, CD34
  • Female
  • Hemangioendothelioma* / diagnostic imaging
  • Hemangioendothelioma* / surgery
  • Hemangioendothelioma, Epithelioid* / diagnostic imaging
  • Hemangioendothelioma, Epithelioid* / surgery
  • Humans
  • Infant
  • Liver
  • Muscle Hypertonia

Substances

  • Antigens, CD34