A Mass on the Sole Revealing a Giant-Cell Tumor of the Tendon Sheath

Skinmed. 2023 Sep 29;21(4):280-281. eCollection 2023.

Abstract

A 61-year-old woman presented with a 3-year history of painless soft-tissue mass on the right sole. The patient reported gradual growth, with a rapid increase in size over the past few months, leading to difficulty in walking. She had no history of past trauma. Examination revealed a 4-cm ovoid mass located over the ball of the foot. It was firm in consistency, with well-defined margins, a smooth surface, and an overlying normal skin (Figure 1). An ultrasound image revealed an eccentric, hypoechoic, nonvascular subcutaneous lobular mass. A magnetic resonance imaging (MRI) of the foot revealed a well-defined mass arising from the flexor tendon sheath of the right foot. The lesion was heterogeneously hyperin-tense on T1- and T2-weighted images with an avid contrast enhancement. All of the surrounding soft tissues indicated normal signal intensity patterns. There was no associated bony destruction. Histopathologic examination after complete excision of the mass established a well-circumscribed lesion composed of osteoclast-like giant cells and mononuclear cells in a hyalinized stroma, consistent with a giant cell tumor of the tendon sheath (GCT-TS) (Figure 2). There was no recurrence during a 6-month follow-up period (Figure 3).

Publication types

  • Case Reports

MeSH terms

  • Female
  • Foot / pathology
  • Giant Cell Tumor of Tendon Sheath* / diagnosis
  • Giant Cell Tumor of Tendon Sheath* / pathology
  • Giant Cell Tumor of Tendon Sheath* / surgery
  • Giant Cell Tumors* / diagnosis
  • Giant Cell Tumors* / pathology
  • Giant Cell Tumors* / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Tendons / diagnostic imaging
  • Tendons / pathology