Novel Material Optimization Strategies for Developing Upgraded Abdominal Meshes

Int J Mol Sci. 2023 Sep 19;24(18):14298. doi: 10.3390/ijms241814298.

Abstract

Over 20 million hernias are operated on globally per year, with most interventions requiring mesh reinforcement. A wide range of such medical devices are currently available on the market, most fabricated from synthetic polymers. Yet, searching for an ideal mesh is an ongoing process, with continuous efforts directed toward developing upgraded implants by modifying existing products or creating innovative systems from scratch. In this regard, this review presents the most frequently employed polymers for mesh fabrication, outlining the market available products and their relevant characteristics, further focusing on the state-of-the-art mesh approaches. Specifically, we mainly discuss recent studies concerning coating application, nanomaterials addition, stem cell seeding, and 3D printing of custom mesh designs.

Keywords: abdominal meshes; composite materials; improved biomedical devices; mesh materials; optimization strategies; polymer materials.

Publication types

  • Review

MeSH terms

  • Abdomen*
  • Nanostructures*
  • Polymers
  • Printing, Three-Dimensional
  • Reinforcement, Psychology

Substances

  • Polymers

Grants and funding

This research received no external funding.