Unilateral Macular hole in a patient with Retinitis Pigmentosa treated with cover flap technique with the use of platelet-rich plasma under air tamponade: case report

Lo Giudice G; Alessandria A; Imburgia A; Anastasi M; Randazzo V; Masaniello F; Pioppo A

doi:10.1097/ICB.0000000000001491

Unilateral Macular hole in a patient with Retinitis Pigmentosa treated with cover flap technique with the use of platelet-rich plasma under air tamponade: case report

Retin Cases Brief Rep. 2023 Sep 19. doi: 10.1097/ICB.0000000000001491. Online ahead of print.

Authors

Lo Giudice G¹, Alessandria A², Imburgia A¹, Anastasi M³, Randazzo V⁴, Masaniello F⁴, Pioppo A¹

Affiliations

¹ Ophthalmic Unit, Department head and neck, ARNAS-Civico Palermo, Italy, Tel. Nr. +393922120826, mail: gregorio.logiudice@hotmail.it.
² Ophthalmic Unit, University of Galati, 80578, Galati, Romania, Tel. Nr. +393516266799, mail: amedeo161@gmail.com.
³ Ophthalmic Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37129 Verona, Italy; Tel .Nr. +393406000619, mail: drmarcoanastasi@gmail.com.
⁴ Ophthalmic Unit, AOOR Villa Sofia - Cervello, Palermo, Italy, Tel. Nr. +393922120826, mail: gregorio.logiudice@hotmail.it.

PMID: 37756670
DOI: 10.1097/ICB.0000000000001491

Abstract

Purpose: The purpose of the study is to show the excellent anatomical result of the inverted flap-assisted technique with PRP under air for retinitis pigmentosa complicated with macular hole.

Methods: A 32-year-old woman, previously diagnosed with retinitis pigmentosa, was referred to our department complaining of decreased central vision in her LEFT eye for 4 weeks. At the time of presentation, the optical coherence tomography and fundoscopy examination showed the presence of a macular hole of 620 microns in diameter. The closure of the macular hole was observed after the surgical procedure, but endophthalmitis occurred 5 days postoperatively.

Results: In our presented case, the cover flap-assisted technique with PRP under air for retinitis pigmentosa complicated with macular hole resulted in excellent anatomical outcomes with unremarkable visual recovery.

Conclusion: The physiopathology of full-thickness macular holes in RP patients remains still not fully elucidated. Pars plana vitrectomy with the adjunct of highly concentrated P-PRP have shown successful results.