Dynamic CZT-SPECT: Characterizing the Lower Values of Myocardial Blood Flow and Reserve

Clin Nucl Med. 2023 Nov 1;48(11):969-970. doi: 10.1097/RLU.0000000000004849. Epub 2023 Sep 18.

Abstract

CZT-SPECT myocardial perfusion enables quantification of myocardial blood flow (MBF). Normal values and thresholds have been accurately defined in PET but remain unclear in SPECT. The aim of this study was to report normal MBF and myocardial flow reserve values in very low-risk patients referred for coronary artery disease screening with dynamic SPECT, in comparison with patients experiencing coronary artery disease. Eighty-four patients (31 male) were analyzed. The mean 10 years risk of fatal cardiovascular events score was 2.7% ± 1.4%. The mean global stress MBF and myocardial flow reserve were 1.6 ± 0.6 mL/min/g and 2.7 ± 0.7.

MeSH terms

  • Coronary Artery Disease* / diagnostic imaging
  • Coronary Circulation
  • Humans
  • Male
  • Myocardial Perfusion Imaging* / methods
  • Myocardium
  • Tomography, Emission-Computed, Single-Photon / methods