Oxidoreductase enzymes: Characteristics, applications, and challenges as a biocatalyst

Biotechnol Appl Biochem. 2023 Dec;70(6):2108-2135. doi: 10.1002/bab.2513. Epub 2023 Sep 27.

Abstract

Oxidoreductases are enzymes with distinctive characteristics that favor their use in different areas, such as agriculture, environmental management, medicine, and analytical chemistry. Among these enzymes, oxidases, dehydrogenases, peroxidases, and oxygenases are very interesting. Because their substrate diversity, they can be used in different biocatalytic processes by homogeneous and heterogeneous catalysis. Immobilization of these enzymes has favored their use in the solution of different biotechnological problems, with a notable increase in the study and optimization of this technology in the last years. In this review, the main structural and catalytical features of oxidoreductases, their substrate specificity, immobilization, and usage in biocatalytic processes, such as bioconversion, bioremediation, and biosensors obtainment, are presented.

Keywords: bioconversion; dehydrogenases; immobilization; oxidases; oxygenases; peroxidases.

Publication types

  • Review

MeSH terms

  • Biodegradation, Environmental
  • Biotechnology
  • Enzymes, Immobilized / chemistry
  • Oxidoreductases* / chemistry
  • Peroxidases*

Substances

  • Oxidoreductases
  • Peroxidases
  • Enzymes, Immobilized