Objective: To evaluate the effect of comprehensive intervention model based on key persons in entertainment venues on the incidence of AIDS-related high-risk behaviors in male sex workers (MSW). Data from this study thus can be used to provide compelling evidence for the wider implementation of the intervention model. Methods: In this randomized controlled trial, MSW were recruited and followed-up from May to December, 2021 in entertainment venues in Wuxi, Jiangsu Province, with an estimated sample size of 320. The MSW in the intervention group were provided with comprehensive interventions via key persons in entertainment venues compared with the control group receiving routine interventions. The effect of the intervention model was assessed by comparing the behavioral differences between these two groups and in the intervention group before and after intervention. Results: A total of 330 MSW were recruited at baseline survey, in which 168 were divided into intervention group and 162 into control group. There was no significant difference in socio-demographic characteristics between two groups (all P>0.05). After intervention for 6 months, the rate of consistent condom use in commercial homosexual activities in the intervention group was 79.5% (101/127), higher than 63.2% (74/117) in the control group, and in the intervention group, 90.1% (73/81) of MSW used condom consistently in heterosexual activities, higher than in the control group (59.6%, 59/99) . Compared with 30.8% (36/117) of MSW with drug abuse history in the control group, a lower proportion of 9.4% (12/127) was observed in the intervention group. Differences in all of aforementioned variables were significant (all P<0.05). After intervention, the incidence of group sex was 3.9% (5/127) in the intervention group and 9.4% (11/117) in the control group, the incidence of anal sex post-alcohol consumption was 40.2% (51/127) in the intervention group and 32.5% (38/117) in control group, the differences were not significant (all P>0.05). Conclusions: The intervention model based on key persons in entertainment venues could promote consistent condom use in MSW in both commercial homosexual and heterosexual activities and help them reduce drug abuse, but had no significant effect on decreasing group sex and anal sex after alcohol consumption. It is crucial to improve the intervention model according to the specific characteristics of MSW in order to enhance the effects of comprehensive intervention.
目的： 评估基于娱乐场所关键人物的干预模式，对男性性工作者（MSW）艾滋病高危行为的综合干预效果，为干预模式的推广提供依据。 方法： 2021年5-12月，选取无锡市MSW从业的娱乐场所招募和随访研究对象，开展随机对照试验，估算总样本量为320人。干预组接受由娱乐场所关键人物实施的综合干预措施，对照组接受常规的干预措施。通过比较干预前后组间和干预组组内研究对象的行为差异，评估干预模式效果。 结果： 基线招募MSW 330人，其中干预组168人，对照组162人，两组间人口社会学特征差异无统计学意义（均P>0.05）。干预6个月后，干预组发生同性商业性行为坚持使用安全套的占79.5%（101/127），高于对照组的63.2%（74/117）；干预组发生异性性行为坚持使用安全套的占90.1%（73/81），高于对照组的59.6%（59/99）；干预组有药物滥用史的占9.4%（12/127），低于对照组的30.8%（36/117），差异有统计学意义（均P<0.05）。实施干预后，干预组发生群交的占3.9%（5/127）、发生酒后肛交的占40.2%（51/127），与对照组发生群交的占9.4%（11/117）、发生酒后肛交的占32.5%（38/117），差异无统计学意义（均P>0.05）。 结论： 基于娱乐场所关键人物的干预模式，能够促进MSW在发生同性商业性行为和异性性行为中坚持使用安全套，并减少药物滥用，但对群交和酒后肛交的干预效果不显著。有必要结合该人群特点优化干预模式，以进一步提高综合干预效果。.