Photodegradation for different dissociated species of norfloxacin and ofloxacin in water ice under solar irradiation

Zhuojuan Li; Jing Zhang; Deming Dong; Liwen Zhang; Heyang Sun; Yakun Wang; Zujian Sun; Sinan He; Zhiyong Guo

doi:10.1016/j.jhazmat.2023.132595

Photodegradation for different dissociated species of norfloxacin and ofloxacin in water ice under solar irradiation

J Hazard Mater. 2024 Jan 5:461:132595. doi: 10.1016/j.jhazmat.2023.132595. Epub 2023 Sep 20.

Authors

Zhuojuan Li¹, Jing Zhang², Deming Dong², Liwen Zhang², Heyang Sun², Yakun Wang², Zujian Sun², Sinan He³, Zhiyong Guo⁴

Affiliations

¹ Key Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin Provincial Key Laboratory of Water Resources and Environment, College of New Energy and Environment, Jilin University, Changchun 130012, China; School of Applied Chemistry and Materials, Zhuhai College of Science and Technology, Zhuhai 519040, China.
² Key Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin Provincial Key Laboratory of Water Resources and Environment, College of New Energy and Environment, Jilin University, Changchun 130012, China.
³ Key Laboratory of Urban Environment and Health, and Health Key Laboratory of Urban Metabolism of Xiamen, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: snhe@iue.ac.cn.
⁴ Key Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin Provincial Key Laboratory of Water Resources and Environment, College of New Energy and Environment, Jilin University, Changchun 130012, China. Electronic address: zyguo@jlu.edu.cn.

PMID: 37741203
DOI: 10.1016/j.jhazmat.2023.132595

Abstract

Ice is an important medium that regulates the transformation of organic contaminants. Nonetheless, photodegradation of emerging fluoroquinolone (FQ) antibiotics in the ice, particularly those with varying dissociated species, remains inadequately explored. In this study, the photodegradation of norfloxacin (NOR) and ofloxacin (OFL) in different dissociated species in water ice were investigated. Results indicated that the quantum yield of the zwitterion for NOR in the ice was 1.7-5.0 times higher than that of the cation, and 1.3 times higher than that of the anion. The quantum yield of the zwitterion for OFL in the ice was 2.5-3.4 times higher than that of the cation, and 1.4 times higher than that of the anion. The degradation pathways of NOR and OFL with different dissociated species depended on their molecular structure. Most products possessed lower developmental toxicity than parent NOR and OFL, respectively. OFL showed a higher inhibitory rate of Escherichia coli activity at the initial time of photodegradation, which was higher than that of NOR. This study offers novel insights into the impact of dissociated species on the photodegradation of FQs in ice and contributes to understanding the environmental behavior of fluorinated pharmaceuticals in the cryosphere.

Keywords: Antibiotic; Cryosphere; Emerging contaminant; Photodegradation; Speciation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemistry
Cations
Fluoroquinolones / chemistry
Ice
Norfloxacin* / chemistry
Ofloxacin / chemistry
Photolysis
Water Pollutants, Chemical* / chemistry

Substances

Norfloxacin
Ofloxacin
Anti-Bacterial Agents
Ice
Fluoroquinolones
Cations
Water Pollutants, Chemical