Tafasitamab and lenalidomide in large B-cell lymphoma: real-world outcomes in a multicenter retrospective study

Blood. 2023 Dec 28;142(26):2327-2331. doi: 10.1182/blood.2023021274.

Abstract

In this real-world evaluation of tafasitamab-lenalidomide (TL) in relapsed or refractory LBCL, patients receiving TL had higher rates of comorbidities and high-risk disease characteristics, and substantially lower progression-free survival and overall survival, compared with the L-MIND registration clinical trial for TL.

Publication types

  • Multicenter Study

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Humans
  • Lenalidomide / therapeutic use
  • Lymphoma, Large B-Cell, Diffuse* / drug therapy
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Lenalidomide
  • tafasitamab