Food Allergens of Plant and Animal Origin: Classification, Characteristics, and Properties

Methods Mol Biol. 2024:2717:1-14. doi: 10.1007/978-1-0716-3453-0_1.

Abstract

Food allergy is an adverse immune response to specific foods that can be either IgE-mediated or non-IgE mediated. The causes of IgE-mediated food allergy are multifactorial and involve genetic, dietary, and environmental factors. The prevalence of food allergy has increased over the last few decades, especially in urbanized, industrialized, and Westernized countries, and the epithelial barrier hypothesis has been recently suggested as a possible explanation for this increase. Food allergens of plant and animal origin are classified into a few families and superfamilies that are widely distributed and conserved. While it is known that food allergens share common properties, such as stability to enzymes and solubility, they also exhibit differential properties, and exceptions to the common characteristics exist. In recent years, novel characteristics of food allergens have been proposed based on their immunological properties and their ability to act as adjuvants or enhancers of the immune system.This chapter provides an overview of the current knowledge of food allergy, covering their prevalence, classification of food allergens from plant and animal origins, and recent advancements in the characterization of the properties of these allergens.

Keywords: Allergens classification; Allergens families; Food allergen; Food allergen properties; Food allergy; Plant allergens; Prevalence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adjuvants, Immunologic
  • Adjuvants, Pharmaceutic
  • Animals
  • Food
  • Food Hypersensitivity*
  • Humans
  • Solubility

Substances

  • Adjuvants, Immunologic
  • Adjuvants, Pharmaceutic