Pediatric negative pressure pulmonary edema: Case series and review of the literature

Abstract

Introduction: Negative pressure pulmonary edema (NPPE) is a potentially life-threatening complication that develops rapidly following acute upper airway obstruction. The condition is rare, dramatic but resolves quickly. Prompt recognition and appropriate supportive treatment may prevent unnecessary investigations and iatrogenic complications.

Methods: We describe a spectrum of etiologies and clinical manifestation of pediatric NPPE in our center and review of previous publications.

Conclusion: The etiology for the development of NPPE in children has shifted over the years. Although dramatic in presentation, this type of pulmonary edema often resolves quickly with minimal support.

Keywords: negative pressure pulmonary edema; post-obstruction edema; strangulation; upper airway obstruction.